Modi Laboratary

Gamma Radiation Stearilization

Gamma Radiation Sterilization
Almost all medical products that are covered in schedule C and C1 are commonly sterilized by gamma radiation. An indicative list of these products is given below:

  • Surgical Disposables : Surgical Sutures, Bandages, Dressings, Gauge pads, Nappies, Delivery Kits etc, which are made of Cotton Wool and Gauge.
  • Metallic Products: Surgical Blades, Needles, Implants, Aluminum Caps, Containers etc.
  • Plastic And Rubber Items: Petri-dish, Centrifuge Tube, Blood Collection Sets, Scalp Vein Sets, Shunt Valves, Rubber Gloves, Contraceptive Devices, Gowns, Wraps Covers, Sheets, etc.
  • Pharmaceuticals: Silver Sulphadiazene Cream, Gelatin Capsule, Bentonite Charcoal, Ergot Powder, Absorbable gelatin, Ophthalmic preparations in paraffin base and oil base, Skin Ointment in Polyethylene glycol base.
  • Ayurvedic: Raw Materials, Herbs, Medicines, Granules.
  • Spices : Whole and in Processed form
Requirements of The Products For Irradiation
Packing To be packed in standard 5 ply corrugated card board cartons of outer dimension: 59cm L x 43cm x 33cm. (H)
Weight of box For 25 kGy irradiation dose, (usually health care products), the maximum weight of the box should not exceed 15.0 kg
  For 15 kGy irradiation dose, (usually herbal and ayurvedic products) the maximum weight of the box can be upto 30.0 kg
Documents The consignment should be submitted with a covering order specifying the product detail and irradiation dose* requirement,
Charges The irradiation charges are to be submitted at the time of placing the order, unless alternate agreement is in place. The charges vary from product to product, and you can have a quote for the exact charges by. emailing our product detail to This email address is being protected from spambots. You need JavaScript enabled to view it.
Regulatory consent for drug items For products that are under the purview of Drug Control Authority, a 'Loan License' from the authority I and an undertaking on prescribed format is a prerequisite
Any variation in the above parameters if required can be discussed before sending the consignment

* The irradiation dose should be selected such that it is sufficient for effecting the expected benefits (sterilization, cross- linking etc.) while the adverse effects (degradation, loss of medical efficacy, physical strength etc.) are minimal. If the optimal dose is not known, SARC can undertake dose optimization studies to help the new customers.

The Gamma Sterilization Advantage
Industrial scale sterilization can be done by several techniques such as dry heating, autoclaving (steam' sterilization), gas sterilization (eg. Ethylene oxide sterilization) etc., besides sterilization using gamma rays. But the sterilization using gamma rays has the following advantages:

  • Unlike heat sterilization or steam sterilization, Gamma ray sterilization does not significantly increase the temperature of the products and therefore can be used to sterilize safely even the heat sensitive materials as well as materials in frozen condition.
  • Unlike Ethylene oxide sterilization, gamma sterilization does not leave any harmful residue. In products exposed to gamma rays from Cobalt-60 source at the normally used dose level, there is no danger of radioactivity or toxicity. Radiation processed products does not become radioactive- just as our body do not start emitting X -rays after being X-rayed.
  • Gamma sterilization is performed after packaging of the products in the final containers and does not involve any aseptic handling. Product sterility is retained indefinitely, as long as the packaging is intact
  • Sterilization of products of any shape can be achieved due to the high penetration ability of gamma rays.
  • Gamma ray sterilization is non-polluting, environment friendly process, and since it is a continuous process, the results are more uniform than gas or high temperature sterilization, which are essentially batch processes